Synthesis of thioamides via one-pot A(3)-coupling of alkynyl bromides, amines, and sodium sulfide.
نویسندگان
چکیده
We herein describe a novel method for the synthesis of thioamides by a three component condensation of alkynyl bromides, amines, and Na2S·9H2O. The developed method is applicable for a wide range of amines and alkynyl bromides bearing different functional groups furnishing the corresponding products in moderate to excellent yields.
منابع مشابه
One-pot synthesis of benzolactones and lactams via a cobalt-catalyzed regioselective [2 + 2 + 2] cocyclotrimerization of alkynyl alcohols and amines with propiolates.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 4 شماره
صفحات -
تاریخ انتشار 2014